Conventional Options Gout is traditionally managed with medication, such as nonsteroidal anti-inflammatory drugs (NSAIDs). However, any medication, whether it is by prescription or not, can have serious side effects that may outweigh its benefits.
1 Although medications temporarily ease pain, many become less effective over time.
2 Prescription gout medication can be very addictive.
3 NSAIDs can cause gastrointestinal bleeding and ulcers.
4 A common alternative to NSADs is a Perscription medication, which carries side effects such as nausea, vomiting, and diarrhea.
5 An alternative to some gout prescriptions is corticosteroid medication, which may leech bone marrow, cause poor wound healing, or decrease your ability to fight infection.
6 Some medication can cause severe allergic reactions.
7 All medication brings increased risk of drug interactions.
Gout must be treated in both the short and long term. The inflammation caused by an acute gout attack is painful and can adversely affect one’s daily life. Common treatments for these attacks include NSAIDs, Colchicine, or Corticosteroids. It is important to know the benefits of each and to be wary of the adverse effects of each medicine.
-Relieves pain of acute gout attack
-Specifically targets inflammation in joints
-May cause diarrhea, nausea, or abdominal pain
-Dangerous to those who have history of kidney and liver problems
-Interacts with many type sof medicine such as antidpressants, tranquilizers, or antihistamines
-Intricate dosing requires care to avoid side effects
NSAIDs(Nonsteroidal anti-inflammatory drugs)
NSAID’s are the most commonly used drugs in treatment of Gout inflammation
-NSAID’s are the most commonly used drugs in treatment of Gout inflammation
-Reduces inflammation during acute gout attack
-Does not require Prescription
-May cause ulcers,kidney failure, or liver failure with continued use
-Should not be taken if history of liver and kidney problems
-Can be applied directly to swollen joint via Injection or taken orally
-Can be taken by patients with kidney or liver problems
-Requires scheduled tapering of dosages
-mood, blood pressure, and diabetic control are altered in short term
-may cause cataracts and/or osteoporosis in long term
To prevent future gout flare ups, doctor also often prescribe a medicine to reduce Uric acid levels in the blood. Allopurinol, Probenecid, and Pegloticase are common medications used in reducing serum uric acid levels.
-Most used therapy for uric acid reduction
-Inhibits production of uric acid from purines
-Can be used in patients with kidney problems
-May cause diarrhea, stomach pain, or rash
-Complex dosing requires careful monitoring
-Interacts with diuretics, ampicillin, and ACE inhibitors amongst other drugs
-Increase excretion of uric acid through urination
-Prevents uric acid from reentering the bloodstream
-Patients must increase daily intake of water while taking medication
-May cause complications for patients with history of kidney problems
-Can treat severe gout that is not responding to other medications
-Metabolizes Uric acid to allantoin which is five times more soluble
- Cannot be used in patients with G6PD deficiency
-Must be given intravenously every two weeks